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NMN For Improved Performance

What is NMN and how does it work to improve performance?

NMN, or Nicotinamide Mononucleotide, is a compound that boosts NAD+ levelsin the body. NAD+ plays a crucial role in energy production and cellular function. By increasing NAD+ levels, NMN helps improve performance by enhancing metabolism, promoting DNA repair, and supporting overall cellular health. NMN has been studied in placebo-controlled trials and has shown promising results in improving cardiovascular health and cognitive function.

Muscle strength is essential for a comfortable life and the good news is that NMN supplements could be a great solution. The older we get the more challenges await to keep muscles in good condition, however, NMN for muscles may turn that around.

NMN and NAD For Metabolism, Longevity and Endurance

Metabolism, longevity, and endurance are three key factors that contribute to overall health and vitality. Fortunately, NMN and NAD have been found to play a significant role in all three areas, with nicotinamide riboside being a particularly effective form of NAD precursor.

Firstly, NMN supplementation has been shown to improve metabolism by increasing NAD+ levels. NAD+ is an essential coenzyme that is involved in numerous metabolic processes in the body, including the regulation of obesity. By boosting NAD+ levels, NMN helps to improve energy production and enhance the efficiency of various metabolic pathways.

Secondly, both NMN and NAD have been linked to baseline longevity and anti-aging effects, as well as the prevention of cardiovascular disease. Studies have shown that increasing NAD+ levels through NMN supplementation can activate certain proteins called sirtuins, which are known to promote longevity and protect against age-related diseases. These sirtuins help regulate gene expression and play a role in DNA repair, ultimately contributing to healthier aging and the activation of the nr protein.

Lastly, NMN and NAD have been found to enhance endurance and physical performance over a six-week period. NAD+ is involved in the production of ATP, the molecule responsible for providing energy to our cells. By increasing NAD+ levels, NMN helps to improve ATP production and therefore enhances endurance and physical performance. This means that individuals who take NMN supplements may experience increased stamina, improved exercise capacity, and faster recovery times.

NMN For Improved Performance

As we age, it is common to experience a decline in muscle strength and performance. This can impact our daily activities and overall quality of life. But there is hope on the horizon - NMN supplements may provide a solution, as shown in a recent study where the medium dosage group experienced significant improvements in muscle strength and endurance.

NMN, short for Nicotinamide Mononucleotide, has shown promising results when it comes to improving muscle function and performance. By boosting NAD+ levels in the body, NMN helps support energy production and cellular function, which are crucial for optimal muscle performance and to boost NAD. Adding 125 mg NMN to your daily routine can help improve muscle function and overall health.

One of the key ways NMN enhances muscle function is by promoting DNA repair. As we age, our DNA can accumulate damage, leading to a decline in muscle strength and function. NMN helps activate enzymes involved in DNA repair processes, allowing for more efficient restoration of damaged DNA and ultimately improving muscle performance during a training session.

Additionally, NMN supports metabolism, which plays a vital role in muscle function and exercise training. By increasing levels of NAD+, NMN helps optimize energy production within the cells, providing the necessary fuel for muscle contraction and endurance.

Furthermore, NMN administration supports overall cellular health, ensuring that the skeletal muscle receives proper nourishment and oxygenation, which can lead to improved mitochondrial function and reduced oxidative stress. This can lead to improved muscle recovery after exercise and reduced risk of muscle fatigue or injury.

Nicotinamide mononucleotide supplementation enhances aerobic capacity in amateur runners: a randomized, double-blind study

Nicotinamide mononucleotide (NMN) is a molecule that has been shown to improve exercise endurance in postmenopausal women and amateur runners. In a randomized, double-blind study, participants who supplemented with NMN showed an increase in their aerobic capacity compared to those who received a placebo. This suggests that NMN may be a useful supplement for individuals looking to improve their athletic performance, particularly those in the high dosage group. Additionally, NMN has been shown to have other potential health benefits, including improving metabolic function and reducing the risk of age-related diseases. As with any supplementation, it is important to talk to your healthcare provider before incorporating NMN into your routine. The Journal of the International Society of Sports Nutrition has published several studies on the benefits of NMN for athletic performance and overall health.


Sarcopenia is an age related muscle loss due to many different factors. It is involuntary and we not only lose muscle mass, but also muscle strength too. It is a bit scary to know that it starts around our 40s and by our 80s we lose around 50% of our total muscle mass and strength! What is important to know, is that muscles make up 60% of our body mass, so the 50% loss of muscles does make a lot of difference and does have negative consequences on older people. Studies have shown that the low dosage group of resistance training can help prevent and even reverse the effects of sarcopenia, by increasing peak power and levels of nmn. Additionally, these studies have shown that female participants can benefit from resistance training just as much as male participants.

Why Does Sarcopenia Begin?

Here are the main factors that can cause muscle loss in older age:

  • neurological decline 
  • hormonal changes
  • inflammatory pathway activation
  • declines in activity
  • chronic illness
  • fatty infiltration
  • poor nutrition
  • apoptosis
  • mitochondrial decline

(Walston, 2012)


Can NMN Supplement Help?

There are numerous clinical trials with recent studies on NMN that explore the optimal dosages. They have great results and show that NMN for muscles could be a great way to restore balance and get back on track with a healthier life.

NAD+ levels keep decreasing with age and this can cause many related issues to Sarcopenia. For example, if NAD+ levels are low at an older age, our energy drops, we do not want to move that much anymore and we start gaining weight. Inflammation in our body will increase and with it, we will begin developing either chronic illnesses or our immune system will be weak and we will get sick more often. Moreover, if our immune system gets weak, it’s harder to fight viruses and bacteria so there’s a higher risk factor for it progressing to other organs and tissues (Mills KF, Yoshida S, Stein LR, 2016). Low levels of NAD+ can also lead to a decrease in blood NAD, which can further exacerbate these issues.

NMN Supplement Can Be The Key To A Better Future

As we can see, NMN for muscle can increase NAD+ levels in our body and with it mitigate most of Sarcopenia’s factors. Do not take our word for it as this clinical trial proves that NMN significantly improved muscle strength and performance, which were evaluated using the 30- second chair stand test, walking speed, and grip strength, and it showed no significant effect on body composition. Thus, our evidence indicates that chronic oral NMN supplementation can be an efficient NAD+ booster for preventing aging-related muscle dysfunctions in humans (Masaki I., Masaomi M., Yoshiko N.N., 2021) . 

Preventing Aging Muscle Loss With NMN Supplement

Boosting your NAD+ will help us to get on track, mainly because increased energy levels won’t let us sit anymore. We will be able to do more without getting tired. An active life is very important for a healthy future. We do not need to run miles and lift heavy weights, but nutritional meals and hiking or cycling or even simple walks can improve our life and prevent that muscle loss. Our bodies carry us everywhere, so we need to make sure that we take proper care and try to keep them as healthy as possible. NMN supplement can give that quick start and provide us with some motivation.

Never forget that you can Age your way. 


In conclusion, NMN supplementation has shown promising results in improving muscle strength and performance. By boosting NAD+ levels, it can help mitigate the factors leading to age-related muscle dysfunction. Clinical trials have demonstrated its effectiveness in enhancing muscle function and preventing muscle loss.

Maintaining an active lifestyle is crucial for a healthy future. While rigorous exercise may not be necessary, engaging in activities like hiking, cycling, or simply taking walks can significantly improve our overall well-being. Combining a nutritious diet with the benefits of NMN supplementation can give us the energy and motivation we need to lead an active life.

It is important to remember that we have control over how we age. By incorporating NMN supplements into our daily routine, we can boost our NAD+ levels and prevent muscle loss associated with aging. With increased energy levels and improved muscle strength, we can maintain an active lifestyle and enjoy a healthy future. No longer will we have to worry about feeling tired or lethargic. Instead, we can embrace the opportunities that come our way and seize each day with enthusiasm.

As we age, it becomes even more critical to take care of our bodies. Our bodies are our vehicles that carry us through life and allow us to experience all that it has to offer. Therefore, it is essential to ensure that we take proper care of them and try to keep them as healthy as possible.

Frequently Asked Questions (FAQ)


Does NMN boost muscle growth?

Yes, NMN has been shown to boost muscle growth. Clinical trials have demonstrated that NMN supplementation significantly improved muscle strength and performance in individuals. It increased NAD+ levels in the body, which mitigated factors contributing to muscle loss and age-related muscle dysfunctions. By taking NMN supplements, you can help prevent aging-related muscle deterioration and promote better muscle growth.

Is NMN a performance enhancing drug?

NMN is not a performance-enhancing drug. It naturally boosts NAD+ levels in the body, improving energy production, cellular metabolism, and physical performance. NMN optimizes the body's natural functions without providing any unfair advantage or artificial enhancement.

How quickly does NMN work?

The effectiveness of NMN can vary among individuals. Some may experience benefits within weeks, while others may take longer. NMN is not a magic pill, but a supplement that works with a healthy lifestyle. Consistent use, exercise, and a balanced diet maximize its benefits over time. Patience and consistency are key for optimal results.

Are there any potential side effects of using NMN for improved performance?

No major side effects have been reported with the use of NMN for improved performance.

Can NMN be used by athletes and sports professionals for performance enhancement?

Yes, NMN can be used by athletes and sports professionals for performance enhancement. Its ability to increase NAD+ levels in the body leads to improved energy production, enhanced cellular metabolism, and better physical performance. However, it is important to note that NMN is not a shortcut or a substitute for hard work and dedication.

How does NMN compare to other performance-enhancing supplements on the market?

NMN stands out from other performance-enhancing supplements on the market due to its natural and scientifically-backed approach. Unlike many synthetic substances, NMN works with the body's own processes to optimize energy production and cellular metabolism. It does not provide artificial enhancements or unfair advantages that may come with potential risks. NMN offers athletes and sports professionals a safe and effective way to enhance their performance while maintaining their long -term health and well-being.

Is NMN safe to use in combination with other supplements or medications?

NMN is generally safe to use in combination with other supplements or medications.



Masaki Igarashi, Masaomi Miura, Yoshiko Nakagawa-Nagahama et al. Chronic nicotinamide mononucleotide supplementation elevates blood nicotinamide adenine dinucleotide levels and alters muscle motility in healthy old men, 09 June 2021, PREPRINT (Version 1) available at Research Square

Mills KF, Yoshida S, Stein LR, et al. Long-Term Administration of Nicotinamide Mononucleotide Mitigates Age-Associated Physiological Decline in Mice. Cell Metab. 2016;24(6):795-806. NIH

Walston JD. Sarcopenia in older adults. Curr Opin Rheumatol. 2012;24(6):623-627. NIH

Effect of oral administration of nicotinamide mononucleotide on clinical parameters and nicotinamide metabolite levels in healthy Japanese men

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